Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31439585 | 0.85 | ALDH1A1 (0.38) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL21807443 | 0.81 | GPR119 (0.49) | GPR119JAK2JAK1 | |
| SCHEMBL28504730 | 0.81 | GPR119 (0.49) | GPR119JAK2JAK1 | |
| SCHEMBL1498927 | 0.81 | GPR119 (0.49) | GPR119JAK2JAK1 | |
| SCHEMBL23235715 | 0.81 | SLC6A9 (0.44) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL13812253 | 0.81 | SLC6A9 (0.44) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL20454638 | 0.80 | USP2 (0.42) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL29930781 | 0.80 | USP2 (0.42) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL27034020 | 0.80 | MEN1 (0.43) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL26537600 | 0.80 | MEN1 (0.43) | MEN1ALDH1A1MAPTKMT2ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025015167-A2 | ERASTIN KETONE ANALOGS AND USES THEREOF | EXARTA THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |