Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.49 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL652791 | 0.83 | LMNA (0.79) | LMNAPOLBSIGMAR1GRM7 | |
| SCHEMBL21624677 | 0.82 | SIGMAR1 (0.55) | LMNASIGMAR1KDM1A | |
| SCHEMBL21624674 | 0.82 | SIGMAR1 (0.55) | LMNASIGMAR1KDM1A | |
| Hydrochloric Acid SCHEMBL6473105 | 0.82 | LMNA (0.77) | LMNAPOLBSIGMAR1GRM7 | |
| SCHEMBL34468348 | 0.80 | SIGMAR1 (0.52) | LMNAPOLBSIGMAR1KDM1A | |
| SCHEMBL15054874 | 0.80 | SIGMAR1 (0.52) | LMNAPOLBSIGMAR1KDM1A | |
| SCHEMBL34468338 | 0.80 | EPHX2 (0.62) | SIGMAR1KDM1A | |
| SCHEMBL30718482 | 0.80 | EPHX2 (0.62) | SIGMAR1KDM1A | |
| SCHEMBL15055182 | 0.80 | EPHX2 (0.62) | SIGMAR1KDM1A | |
| Trifluoroacetic Acid SCHEMBL5037867 | 0.79 | POLB (0.52) | LMNAPOLBSSTR4HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025015167-A2 | ERASTIN KETONE ANALOGS AND USES THEREOF | EXARTA THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |