Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 3/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3768581 | 0.99 | FYN (0.37) | FYNMAP4K4CHRNB1CHRNB2CHRNB4 | |
| SCHEMBL3155137 | 0.88 | MAP4K4 (0.35) | FYNMAP4K4CHRNB1CHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL3770439 | 0.87 | MAP4K4 (0.35) | FYNMAP4K4CHRNB1CHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL3773421 | 0.86 | DHFR (0.36) | FYNUSP7 | |
| SCHEMBL3154920 | 0.86 | MAP4K4 (0.35) | FYNMAP4K4CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL3781375 | 0.86 | ABL1 (0.34) | FYNABL1 | |
| Hydrochloric Acid SCHEMBL3776437 | 0.85 | MAP4K4 (0.35) | FYNMAP4K4CHRNB4CHRNA3 | |
| SCHEMBL3137015 | 0.84 | ABL1 (0.37) | MAP4K4KITUSP7SMN1; SMN2ABL1 | |
| Hydrochloric Acid SCHEMBL3776994 | 0.82 | MAP4K4 (0.38) | FYNMAP4K4CHRNB1CHRNB2CHRNB4 | |
| SCHEMBL3770703 | 0.80 | SMN1; SMN2 (0.33) | USP7SMN1; SMN2ABL1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |