Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 3/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3770439 | 0.99 | MAP4K4 (0.35) | MAP4K4FYNCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL3144019 | 0.88 | FYN (0.37) | MAP4K4FYNCHRNB1CHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL3768581 | 0.87 | FYN (0.37) | MAP4K4FYNCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL3146709 | 0.87 | CHRNB2 (0.41) | CHRNB2 | |
| SCHEMBL3150790 | 0.87 | PRKCZ (0.32) | — | |
| Hydrochloric Acid SCHEMBL3774047 | 0.86 | CHRNB2 (0.41) | CHRNB2 | |
| Hydrochloric Acid SCHEMBL3770716 | 0.86 | CHRNB2 (0.41) | CHRNB2 | |
| SCHEMBL3154920 | 0.86 | MAP4K4 (0.35) | MAP4K4FYNCHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL3774548 | 0.86 | PRKCZ (0.32) | — | |
| Hydrochloric Acid SCHEMBL3776437 | 0.85 | MAP4K4 (0.35) | MAP4K4FYNCHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |