Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3147209 | 0.89 | ABL1 (0.39) | ABL1EGLN1CYP4A11 | |
| SCHEMBL3260960 | 0.85 | EGLN1 (0.40) | KDM4EALDH1A1EGLN1 | |
| SCHEMBL3144019 | 0.84 | FYN (0.37) | ABL1SMN1; SMN2MAOAKITUSP7 | |
| SCHEMBL3154853 | 0.84 | CHRNB2 (0.45) | ABL1MAP4K4 | |
| Hydrochloric Acid SCHEMBL3768581 | 0.83 | FYN (0.37) | ABL1SMN1; SMN2MAOAKITUSP7 | |
| SCHEMBL3147340 | 0.82 | MAP4K4 (0.37) | ABL1EGLN1MAP4K4 | |
| SCHEMBL3770703 | 0.82 | SMN1; SMN2 (0.33) | ABL1SMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL3770701 | 0.80 | ABL1 (0.36) | ABL1SMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL3141819 | 0.80 | EGLN1 (0.48) | EGLN1 | |
| SCHEMBL3137025 | 0.80 | SMN1; SMN2 (0.36) | ABL1SMN1; SMN2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |