Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139624 | 0.86 | RAB9A (0.54) | RAB9AFDPSCYP2A6ALDH1A1AOX1 | |
| SCHEMBL3136365 | 0.83 | RAB9A (0.51) | RAB9AFDPSCYP2A6ALDH1A1AOX1 | |
| SCHEMBL4064508 | 0.82 | ALDH1A1 (0.45) | RAB9AFDPSCYP2A6PTGER4ALDH1A1 | |
| SCHEMBL3153633 | 0.78 | GBA1 (0.38) | RAB9ANPC1LMNAPTPN1RAD52 | |
| SCHEMBL25473421 | 0.78 | CYP1A2 (0.50) | RAB9ACYP2A6TDP1CYP1A2 | |
| SCHEMBL8370814 | 0.76 | CYP1A2 (0.44) | RAB9ACYP2A6TDP1CYP1A2PTPN1 | |
| SCHEMBL3135691 | 0.75 | CYP2A6 (0.47) | RAB9ACYP2A6ALDH1A1NPC1MAPT | |
| SCHEMBL7181020 | 0.75 | RAB9A (0.49) | RAB9AFDPSCYP2A6ALDH1A1AOX1 | |
| SCHEMBL29195519 | 0.74 | CYP2A6 (0.53) | RAB9ACYP2A6ALDH1A1AOX1TSHR | |
| SCHEMBL3144937 | 0.73 | L3MBTL1 (0.34) | CYP2D6PTPN1RAD52PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081825-A1 | 1-NAPHTHYL ALKYLPIPERIDINE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2010-04-01 | — | — | US | disclosed |
| CN-101595091-A | 1-naphthyl alkylpiperidine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-12-02 | — | — | CN | disclosed |
| EP-2098509-A1 | 1-NAPHTHYL ALKYLPIPERIDINE DERIVATIVE | Taisho Pharmaceutical Co. Ltd. (JP) | 2009-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081825-A1 | 1-NAPHTHYL ALKYLPIPERIDINE DERIVATIVE | MCHR1, MCHR2, MC5R | RAB9A 335/4885FDPS 4356/4885CYP2A6 3059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.