Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16332676 | 0.83 | GPR84 (0.39) | CA1CA2CA9HSD11B1ADORA2A | |
| SCHEMBL20017913 | 0.81 | ADORA2A (0.38) | CA1CA2CA9HSD11B1ADORA2A | |
| SCHEMBL6937413 | 0.80 | HSD11B1 (0.50) | CA1CA2CA9HSD11B1HPGD | |
| SCHEMBL6852343 | 0.79 | NQO1 (0.46) | CA1CA2CA9HSD11B1ADORA2A | |
| SCHEMBL8770833 | 0.79 | CA1 (0.43) | CA1CA2CA9HPGDKDM4E | |
| SCHEMBL26870524 | 0.79 | GPR84 (0.50) | CA1CA2CA9ADORA2AADORA1 | |
| SCHEMBL4456112 | 0.78 | IRAK4 (0.52) | CA1CA2HSD11B1ADORA2AADORA1 | |
| SCHEMBL2654823 | 0.78 | NQO2 (0.49) | CA1CA2CA9HSD11B1ADORA2A | |
| SCHEMBL6937631 | 0.77 | GPR84 (0.45) | CA1CA2CA9ADORA2AADORA1 | |
| SCHEMBL2656359 | 0.76 | NQO2 (0.43) | HSD11B1ADORA2AADORA1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330919-A | Preparation method of 8-bromo-6-phenylnaphtho [2,1-b ] benzofuran | 中钢天源股份有限公司 | 2025-01-21 | — | — | CN | claimed |
| CN-119330919-A | Preparation method of 8-bromo-6-phenylnaphtho [2,1-b ] benzofuran | 中钢天源股份有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-119330919-A | Preparation method of 8-bromo-6-phenylnaphtho [2,1-b ] benzofuran | 中钢天源股份有限公司 | 2025-01-21 | — | — | CN | disclosed |