SCHEMBL31443774

SCHEMBL31443774

CC(C)(C)OC(=O)N1CCN(c2ccc(N3CCC(=O)NC3=O)cc2OS(=O)(=O)F)CC1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 8/20 0.44
▸ CRBN Q96SW2 8/20 0.44
▸ PDK2 Q15119 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ GPR119 Q8TDV5 5/20 0.39
▸ PIK3CA P42336 1/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ SMARCA2 P51531 1/20 0.37
▸ SMARCA4 P51532 1/20 0.37
▸ PBRM1 Q86U86 1/20 0.37
▸ HTT P42858 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31444055 0.85 DDB1 (0.44) DDB1CRBNMAPTGPR119MEN1
SCHEMBL30703627 0.84 DDB1 (0.48) DDB1CRBNPDK2ALDH1A1LMNA
SCHEMBL31443950 0.81 DDB1 (0.39) DDB1CRBNALDH1A1
SCHEMBL31444107 0.81 DDB1 (0.45) DDB1CRBNALDH1A1LMNAMAPT
SCHEMBL31443748 0.81 DDB1 (0.45) DDB1CRBNALDH1A1LMNAMAPT
SCHEMBL31443802 0.81 DDB1 (0.50) DDB1CRBNPDK2GPR119MEN1
SCHEMBL25824549 0.81 DDB1 (0.48) DDB1CRBNPDK2ALDH1A1LMNA
SCHEMBL22119507 0.81 DDB1 (0.59) DDB1CRBNPDK2ALDH1A1LMNA
SCHEMBL30643667 0.80 DDB1 (0.49) DDB1CRBNPDK2ALDH1A1LMNA
SCHEMBL31444018 0.79 DDB1 (0.58) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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