SCHEMBL31443950

SCHEMBL31443950

O=C(O)CN1CCN(c2ccc(N3CCC(=O)NC3=O)cc2OS(=O)(=O)F)CC1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 11/20 0.39
▸ CRBN Q96SW2 11/20 0.39
▸ DRD2 P14416 6/20 0.34
▸ DRD4 P21917 6/20 0.34
▸ DRD3 P35462 6/20 0.34
▸ KDM4E B2RXH2 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ S1PR1 P21453 1/20 0.33
▸ TNKS O95271 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31444132 0.83 DDB1 (0.38) DDB1CRBNDRD4KDM4EALDH1A1
SCHEMBL31443748 0.83 DDB1 (0.45) DDB1CRBNDRD2DRD4DRD3
SCHEMBL31444107 0.83 DDB1 (0.45) DDB1CRBNDRD2DRD4DRD3
SCHEMBL31443774 0.81 DDB1 (0.44) DDB1CRBNALDH1A1
SCHEMBL31443879 0.79 CRBN (0.40) DDB1CRBNDRD2DRD4DRD3
SCHEMBL30678685 0.76 DDB1 (0.58) DDB1CRBNDRD2DRD3KDM4E
SCHEMBL26112661 0.76 DDB1 (0.58) DDB1CRBNDRD2DRD3KDM4E
SCHEMBL31443902 0.74 DDB1 (0.38) DDB1CRBNDRD4KDM4EALDH1A1
SCHEMBL31444154 0.73 DDB1 (0.45) DDB1CRBNDRD4
SCHEMBL31443981 0.69 CRBN (0.58) DDB1CRBNKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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