SCHEMBL31444014

SCHEMBL31444014

O=C(O)CN1CCC(c2ccc(C3CCC(=O)NC3=O)cc2OS(=O)(=O)F)CC1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 16/20 0.40
▸ DDB1 Q16531 13/20 0.40
▸ IKZF2 Q9UKS7 3/20 0.38
▸ IKZF1 Q13422 1/20 0.36
▸ GSPT1 P15170 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443695 0.91 CRBN (0.41) CRBNDDB1IKZF2IKZF1GSPT1
SCHEMBL31443818 0.88 CRBN (0.47) CRBNDDB1IKZF1GSPT1
SCHEMBL31443879 0.85 CRBN (0.40) CRBNDDB1GSPT1
SCHEMBL31443705 0.84 CRBN (0.43) CRBNDDB1IKZF2
SCHEMBL24125788 0.84 CRBN (0.43) CRBNDDB1IKZF2IKZF1
SCHEMBL30120115 0.84 CRBN (0.43) CRBNDDB1IKZF2IKZF1
Hydrochloric Acid SCHEMBL29197710 0.83 CRBN (0.42) CRBNDDB1IKZF2IKZF1
SCHEMBL31444037 0.81 CRBN (0.46) CRBNDDB1
SCHEMBL31443868 0.81 CRBN (0.46) CRBNDDB1
SCHEMBL31444132 0.81 DDB1 (0.38) CRBNDDB1IKZF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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