SCHEMBL31443902

SCHEMBL31443902

CS(=O)(=O)Oc1cc(N2CCC(=O)NC2=O)ccc1C1CCN(CC(=O)O)CC1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 11/20 0.38
▸ CRBN Q96SW2 11/20 0.38
▸ IKZF2 Q9UKS7 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ DRD4 P21917 1/20 0.34
▸ ADAM17 P78536 1/20 0.34
▸ ADAMTS5 Q9UNA0 1/20 0.34
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ CCNT1 O60563 1/20 0.33
▸ CDK9 P50750 1/20 0.33
▸ SCN7A Q01118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31444132 0.91 DDB1 (0.38) DDB1CRBNIKZF2KDM4EALDH1A1
SCHEMBL31443969 0.89 DDB1 (0.45) DDB1CRBNDRD4CDK9
SCHEMBL31444089 0.83 DDB1 (0.43) DDB1CRBN
SCHEMBL31443716 0.82 GPR119 (0.45) DDB1CRBNKDM4E
SCHEMBL25169813 0.81 DDB1 (0.43) DDB1CRBNIKZF2KDM4EALDH1A1
SCHEMBL31444154 0.81 DDB1 (0.45) DDB1CRBNDRD4ADAM17ADAMTS5
SCHEMBL31443695 0.81 CRBN (0.41) DDB1CRBNIKZF2
SCHEMBL31443812 0.79 DDB1 (0.48) DDB1CRBNIKZF2
SCHEMBL31443858 0.79 DDB1 (0.46) DDB1CRBN
SCHEMBL24125639 0.77 DDB1 (0.50) DDB1CRBNDRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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