SCHEMBL31444019

SCHEMBL31444019

O=C1CCN(c2ccc(N3CCNCC3)c(S(=O)(=O)F)c2)C(=O)N1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 7/20 0.45
DDB1 Q16531 6/20 0.45
HTR6 P50406 9/20 0.38
DRD3 P35462 4/20 0.37
DRD2 P14416 2/20 0.36
DRD4 P21917 1/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
IDO1 P14902 1/20 0.34
TDO2 P48775 1/20 0.34
IDO2 Q6ZQW0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31444107 0.83 DDB1 (0.45) CRBNDDB1HTR6DRD3DRD2
SCHEMBL31443748 0.83 DDB1 (0.45) CRBNDDB1HTR6DRD3DRD2
SCHEMBL31437046 0.83 CRBN (0.49) CRBNDDB1DRD3DRD2DRD4
SCHEMBL30726420 0.80 DDB1 (0.49) CRBNDDB1DRD3DRD2DRD4
SCHEMBL27039529 0.80 DDB1 (0.49) CRBNDDB1DRD3DRD2DRD4
SCHEMBL31437047 0.80 DDB1 (0.46) CRBNDDB1
SCHEMBL31443918 0.79 CRBN (0.45) CRBNDDB1HTR6
Hydrochloric Acid SCHEMBL30969032 0.79 DDB1 (0.48) CRBNDDB1DRD3DRD2DRD4
SCHEMBL22119794 0.76 CRBN (0.65) CRBNDDB1HTR6KDM4EALDH1A1
SCHEMBL27039415 0.75 CRBN (0.46) CRBNDDB1HTR6DRD3IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed