Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 3/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31444375 | 0.87 | HSP90AA1 (0.42) | SMOROCK2HSP90AA1HSP90AB1 | |
| SCHEMBL31444445 | 0.85 | RAB9A (0.50) | ROCK2KDM4EALDH1A1HPGDGLA | |
| SCHEMBL31444327 | 0.83 | ROCK2 (0.40) | ROCK2KDM4EALDH1A1HPGDGLA | |
| SCHEMBL31444507 | 0.82 | SMO (0.41) | SMOKDM4EALDH1A1HPGDGLA | |
| SCHEMBL31444398 | 0.82 | NTRK1 (0.41) | ROCK2KDM4EALDH1A1HPGDMAPK10 | |
| SCHEMBL31444262 | 0.81 | SMO (0.41) | SMOKDM4EALDH1A1HPGDGLA | |
| SCHEMBL31444386 | 0.78 | SCN9A (0.42) | ROCK2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL31443696 | 0.77 | SCN9A (0.36) | ROCK2CASP1CASP7HSP90AA1HSP90AB1 | |
| SCHEMBL21732085 | 0.77 | NTRK1 (0.55) | — | |
| SCHEMBL21723127 | 0.77 | NTRK1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |