⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31444379 | 0.84 | NR1H2 (0.44) | — | |
| SCHEMBL26614997 | 0.81 | — | — | |
| SCHEMBL23931000 | 0.80 | FKBP1A (0.31) | — | |
| SCHEMBL20973268 | 0.80 | FKBP1A (0.31) | — | |
| SCHEMBL21906217 | 0.79 | NR1H2 (0.31) | — | |
| SCHEMBL21906221 | 0.79 | — | — | |
| SCHEMBL523945 | 0.77 | MEN1 (0.46) | — | |
| SCHEMBL29239203 | 0.77 | NR1H2 (0.38) | — | |
| SCHEMBL18261305 | 0.77 | — | — | |
| SCHEMBL16096341 | 0.76 | RBP4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |