SCHEMBL29239203

SCHEMBL29239203

CC(C)(C)[Si](C)(C)OCC1CC(CO)CN(C(=O)O)C1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.38
FKBP1A P62942 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2355900 0.85 NR1H2 (0.57) NR1H2
SCHEMBL3841839 0.81 NR1H2 (0.38) NR1H2
SCHEMBL21906217 0.80 NR1H2 (0.31) NR1H2
SCHEMBL16096341 0.80 RBP4 (0.39) FKBP1A
SCHEMBL21193584 0.79 MEN1 (0.43)
SCHEMBL31645669 0.78 EPHX2 (0.34) NR1H2FKBP1A
SCHEMBL1710339 0.78 CA1 (0.39)
SCHEMBL21987460 0.77 FKBP1A (0.36) FKBP1A
SCHEMBL31444448 0.77
SCHEMBL23311099 0.76 NR1H2 (0.32) NR1H2FKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005640-A GCN2 inhibitors and uses thereof 默克专利股份有限公司 2024-05-10 CN disclosed