Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158700 | 0.81 | RXFP1 (0.44) | PTPN1CES2CES1ALDH1A1ALOX15 | |
| SCHEMBL1743414 | 0.81 | CES2 (0.61) | PTPN1CES2CES1ALDH1A1ALOX15 | |
| SCHEMBL30956741 | 0.81 | CES2 (0.61) | PTPN1CES2CES1ALDH1A1ALOX15 | |
| SCHEMBL30547190 | 0.81 | ERCC5 (0.61) | PTPN1CES2CES1ALDH1A1MEN1 | |
| SCHEMBL1199039 | 0.81 | ERCC5 (0.61) | PTPN1CES2CES1ALDH1A1MEN1 | |
| SCHEMBL166429 | 0.80 | PTPN1 (0.58) | PTPN1CES2CES1ALDH1A1ALOX15 | |
| SCHEMBL29844777 | 0.80 | PTPN1 (0.58) | PTPN1CES2CES1ALDH1A1ALOX15 | |
| SCHEMBL29746293 | 0.79 | PTPN1 (0.50) | PTPN1ALDH1A1MEN1KMT2AGSK3B | |
| SCHEMBL31298304 | 0.79 | PTPN1 (0.50) | PTPN1CES2CES1ALDH1A1ALOX15 | |
| SCHEMBL12467964 | 0.79 | ALDH1A1 (0.46) | CES2CES1ALDH1A1ALOX15BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |