Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.58 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.58 |
| ▸ | FEN1 | P39748 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 3/20 | 0.58 |
| ▸ | CES1 | P23141 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.50 |
| ▸ | WNT3A | P56704 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29844777 | 1.00 | PTPN1 (0.58) | PTPN1ERCC5FEN1CES2CES1 | |
| SCHEMBL9409754 | 0.84 | PTPN1 (0.65) | PTPN1CES1ALDH1A1ALOX15GSK3B | |
| SCHEMBL1743414 | 0.83 | CES2 (0.61) | PTPN1ERCC5FEN1CES2CES1 | |
| SCHEMBL30956741 | 0.83 | CES2 (0.61) | PTPN1ERCC5FEN1CES2CES1 | |
| SCHEMBL20508992 | 0.82 | PTPN1 (0.74) | PTPN1ERCC5FEN1CES2CES1 | |
| SCHEMBL30089515 | 0.82 | CTNNB1 (0.68) | PTPN1ERCC5FEN1CES2CES1 | |
| SCHEMBL31298304 | 0.82 | PTPN1 (0.50) | PTPN1ERCC5FEN1CES2CES1 | |
| SCHEMBL31444508 | 0.80 | PTPN1 (0.49) | PTPN1ERCC5FEN1CES2CES1 | |
| SCHEMBL14732971 | 0.80 | CTNNB1 (0.61) | PTPN1ERCC5FEN1CES2CES1 | |
| SCHEMBL8343202 | 0.80 | CES2 (0.60) | PTPN1ERCC5FEN1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 401 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069695-B | Potassium ion competitive acid retarder solid free form and preparation method thereof | 南京道尔医药研究院有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117030876-A | Method for detecting related substances of Fu Nuola raw starting material of fumaric acid | 山东新华制药股份有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-116003260-B | Method for preparing 1-naphthylamine compound from urea derivative and prediction model thereof | 广州国家实验室 | 2023-07-18 | — | — | CN | claimed |
| CN-116003260-A | Method for preparing 1-naphthylamine compound from urea derivative and prediction model thereof | 广州国家实验室 | 2023-04-25 | — | — | CN | claimed |
| CN-109232537-B | Preparation method of Vonoprazan | 迪嘉药业集团有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-105622534-A | Heterocyclic imide derivative containing bisamide structure and preparation method and application thereof | HUBEI BIOPESTICIDE ENG RES CENTER | 2016-06-01 | — | — | CN | claimed |
| CN-105040400-A | Improved cashmere oxidation-reduction bleaching method | NINGXIA ZHONGYIN CASHMERE CO LTD | 2015-11-11 | — | — | CN | claimed |
| EP-3829559-B1 | INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION | MERCK SHARP & DOHME LLC (US) | 2026-05-13 | — | — | EP | disclosed |
| US-20260085046-A1 | Dual Function Compounds For NADPH Oxidase Inhibition And Histone Deacetylase Inhibition | TAIWANJ PHARMACEUTICALS CO LTD (TW) | 2026-03-26 | — | — | US | disclosed |
| US-20250283038-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2025-09-11 | — | — | US | disclosed |
| US-12331044-B2 | Inhibitors of histone deacetylase useful for the treatment or prevention of HIV infection | MERCK SHARP & DOHME LLC (US) | 2025-06-17 | — | — | US | disclosed |
| CN-117285411-B | Preparation method of 2' -bromo-o-fluoro acetophenone | 扬州市普林斯医药科技有限公司 | 2025-03-04 | — | — | CN | disclosed |
| EP-4511027-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | Université Paris Cité (FR) | 2025-02-26 | — | — | EP | disclosed |
| EP-0007716-A1 | R-N-(2-phenyl-2-hydroxyethyl)-3-phenylpropyl amines, their formulations, use and preparation | ELI LILLY AND COMPANY (US) | 1980-02-06 | — | — | EP | disclosed |
| EP-0007204-A1 | Phenethanolamines, their formulations, use and preparation | ELI LILLY AND COMPANY (US) | 1980-01-23 | — | — | EP | disclosed |
| EP-0006766-A1 | Phenethanolamines, their formulations, use and preparation | ELI LILLY AND COMPANY (US) | 1980-01-09 | — | — | EP | disclosed |
| EP-0005783-A1 | Imidazo (2.1-b)-(1.3.4)-thiadiazoles, process for their preparation and their use in medicaments | BAYER AG (DE) | 1979-12-12 | — | — | EP | disclosed |
| US-4153619-A | MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-4124704-A | ANTIMICROBIAL | RIKER LABORATORIES, INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-3965181-A | Tricyclic pharmacological agents, intermediates and methods of making | SYNTEX (U.S.A.) INC. (US) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260085046-A1 | Dual Function Compounds For NADPH Oxidase Inhibition And Histone Deacetylase Inhibition | NOX1, NOX4, CYBB | PTPN1 560/4885ERCC5 2843/4885FEN1 1958/4885 |
| US-12331044-B2 | Inhibitors of histone deacetylase useful for the treatment or prevention of HIV infection | HDAC1, HDAC11, HDAC10 | PTPN1 3249/4885ERCC5 3648/4885FEN1 1687/4885 |
| US-20250283038-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | CXCL10, IL2, IFNG | PTPN1 3497/4885ERCC5 3533/4885FEN1 4385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.