Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15928856 | 0.83 | MME (0.51) | MMEPOLBLMNAMAPTACE | |
| SCHEMBL31447099 | 0.82 | MME (0.46) | MMEPOLBCA2CA4NOD1 | |
| SCHEMBL18263282 | 0.81 | NOD1 (0.39) | MMEPOLBCA2CA4NOD1 | |
| SCHEMBL20212363 | 0.81 | NOD1 (0.39) | MMEPOLBCA2CA4NOD1 | |
| SCHEMBL1912625 | 0.80 | CYP2C9 (0.46) | MMEPOLBCA2CA4NOD1 | |
| SCHEMBL2081023 | 0.80 | CYP2C9 (0.46) | MMEPOLBCA2CA4NOD1 | |
| SCHEMBL7753529 | 0.78 | MME (0.42) | MMEPOLBCA2CA4NOD1 | |
| SCHEMBL15623817 | 0.77 | NOD1 (0.61) | NOD1 | |
| SCHEMBL1133639 | 0.77 | POLB (0.40) | MMEPOLBCA2CA4NOD1 | |
| SCHEMBL8468722 | 0.77 | POLB (0.40) | MMEPOLBCA2CA4NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |