Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | MME | P08473 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20212363 | 1.00 | NOD1 (0.39) | NOD1HDAC2MMECHRM1AKR1A1 | |
| SCHEMBL18263302 | 0.86 | NOD1 (0.34) | NOD1HDAC2CA2 | |
| SCHEMBL18263300 | 0.86 | NOD1 (0.34) | NOD1HDAC2CA2 | |
| SCHEMBL21014407 | 0.86 | NOD1 (0.34) | NOD1HDAC2CA2 | |
| SCHEMBL31299922 | 0.86 | NOD1 (0.34) | NOD1HDAC2CA2 | |
| SCHEMBL18271806 | 0.84 | HDAC2 (0.39) | HDAC2MMEPOLBCA2 | |
| SCHEMBL21014800 | 0.84 | BMP1 (0.34) | — | |
| SCHEMBL31444803 | 0.81 | MME (0.43) | NOD1HDAC2MMEPOLBCA2 | |
| SCHEMBL20232398 | 0.77 | CA2 (0.41) | NOD1HDAC2TDP1CA2SLC6A5 | |
| SCHEMBL10609081 | 0.74 | HDAC2 (0.40) | NOD1HDAC2MMECHRM1AKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199541-A9 | PROCESSES TO PRODUCE BRIVARACETAM | SUZHOU PENGXU PHARMATECH CO. LTD. (CN) | 2024-06-20 | — | — | US | disclosed |
| EP-3302441-B1 | PROCESSES TO PRODUCE BRIVARACETAM | SUZHOU PENGXU PHARMATECH CO LTD (CN) | 2023-12-13 | — | — | EP | disclosed |
| US-11673862-B2 | Processes to produce brivaracetam | SUZHOU PENGXU PHARMATECH CO. LTD. (CN) | 2023-06-13 | — | — | US | disclosed |
| US-20190152908-A1 | PROCESSES TO PRODUCE BRIVARACETAM | ESTEVE QUIMlCA S.A. (ES) | 2019-05-23 | — | — | US | disclosed |
| US-20190152909-A1 | PROCESSES TO PRODUCE BRIVARACETAM | ESTEVE QUIMlCA S.A. (ES) | 2019-05-23 | — | — | US | disclosed |
| US-10221134-B2 | Processes to produce brivaracetam | ESTEVE QUIMICA S.A. (ES) | 2019-03-05 | — | — | US | disclosed |
| US-20180155284-A1 | PROCESSES TO PRODUCE BRIVARACETAM | ESTEVE QUIMlCA S.A. (ES) | 2018-06-07 | — | — | US | disclosed |
| EP-3302441-A1 | PROCESSES TO PRODUCE BRIVARACETAM | Suzhou Pengxu Pharmatech Co., Ltd. (CN) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016191435-A1 | PROCESSES TO PRODUCE BRIVARACETAM | WANG PENG (US) | 2016-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673862-B2 | Processes to produce brivaracetam | BLVRB, CYP3A4, POR | NOD1 2652/4885HDAC2 1186/4885MME 3613/4885 |
| US-20190152908-A1 | PROCESSES TO PRODUCE BRIVARACETAM | BLVRB, CYP3A4, POR | NOD1 2652/4885HDAC2 1186/4885MME 3613/4885 |
| US-10221134-B2 | Processes to produce brivaracetam | BLVRB, CYP3A4, POR | NOD1 2652/4885HDAC2 1186/4885MME 3613/4885 |
| US-20190152909-A1 | PROCESSES TO PRODUCE BRIVARACETAM | BLVRB, CYP3A4, POR | NOD1 2652/4885HDAC2 1186/4885MME 3613/4885 |
| US-20240199541-A9 | PROCESSES TO PRODUCE BRIVARACETAM | BLVRB, CYP3A4, POR | NOD1 2652/4885HDAC2 1186/4885MME 3613/4885 |
| US-20180155284-A1 | PROCESSES TO PRODUCE BRIVARACETAM | BLVRB, CYP3A4, POR | NOD1 2652/4885HDAC2 1186/4885MME 3613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.