SCHEMBL31444810

SCHEMBL31444810

C[C@H](O)C(=O)NCc1cccc(Br)c1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.53
▸ TP53 P04637 1/20 0.53
▸ POLB P06746 1/20 0.53
▸ NPC1 O15118 1/20 0.50
▸ LMNA P02545 2/20 0.49
▸ ALOX5 P09917 1/20 0.49
▸ HPGD P15428 1/20 0.49
▸ MTOR P42345 1/20 0.48
▸ ERAP2 Q6P179 1/20 0.47
▸ ERAP1 Q9NZ08 1/20 0.47
▸ LNPEP Q9UIQ6 1/20 0.47
▸ PTGES O14684 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ ERCC1 P07992 1/20 0.45
▸ ERCC4 Q92889 1/20 0.45
▸ FFAR1 O14842 1/20 0.45
▸ FFAR4 Q5NUL3 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13296168 0.85 MAPT (0.51) MAPTTP53POLBNPC1LMNA
SCHEMBL2747621 0.82 LMNA (0.53) MAPTTP53POLBNPC1LMNA
SCHEMBL7609436 0.81 LMNA (0.52) MAPTTP53POLBNPC1LMNA
SCHEMBL171850 0.80 NPC1 (0.55) MAPTNPC1LMNAALOX5HPGD
SCHEMBL9062437 0.80 KMT2A (0.65) MAPTSMN1; SMN2
SCHEMBL10405578 0.80 KMT2A (0.65) MAPTSMN1; SMN2
SCHEMBL26205760 0.79 MAPT (0.49) MAPTTP53POLBNPC1LMNA
SCHEMBL6225888 0.79 LMNA (0.50) MAPTTP53POLBNPC1LMNA
SCHEMBL1750050 0.78 CYP1A2 (0.58) MAPTTP53NPC1LMNAALOX5
Hydrochloric Acid SCHEMBL20568976 0.78 ALOX5 (0.49) MAPTTP53POLBNPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096710-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 — — WO disclosed
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