Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 4/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 3/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34471563 | 0.83 | KMO (0.35) | KMODAOASPHHCAR2KDM4E | |
| SCHEMBL3971849 | 0.83 | KIF11 (0.36) | SSTR4CNR2 | |
| SCHEMBL16346446 | 0.83 | KMT2A (0.36) | SSTR4L3MBTL1CNR2 | |
| SCHEMBL34471556 | 0.80 | DHODH (0.43) | KMOKDM4EALDH1A1L3MBTL1GAA | |
| SCHEMBL3971002 | 0.79 | GSK3B (0.42) | SSTR4CNR2 | |
| SCHEMBL29008885 | 0.75 | KDM4E (0.44) | KMOASPHHCAR2KDM4EKDM8 | |
| SCHEMBL20928645 | 0.74 | MAPT (0.40) | ASPHHCAR2KDM4EKDM8ALDH1A1 | |
| SCHEMBL286833 | 0.73 | KDM4E (0.55) | KMOASPHKDM4EKDM8ALDH1A1 | |
| SCHEMBL17665467 | 0.73 | RXRA (0.41) | SSTR4NAPRT | |
| SCHEMBL30427548 | 0.73 | RXRA (0.41) | SSTR4NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |