Sugi Predict

Sugi Predict / Compounds / 2-Aminopurine

2-Aminopurine

2-Aminopurine

SCHEMBL3144589

Nc1ncc2[nH]cnc2n1.[Tl]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.96
▸ RXFP1 Q9HBX9 1/20 0.72
▸ KDM4E B2RXH2 2/20 0.57
▸ PDPK1 O15530 1/20 0.47
▸ GDA Q9Y2T3 1/20 0.47
▸ CDK2 P24941 9/20 0.45
▸ DPP4 P27487 1/20 0.44
▸ PAK1 Q13153 1/20 0.42
▸ CDK1 P06493 7/20 0.41
▸ CCNB1 P14635 7/20 0.41
▸ CCNT1 O60563 1/20 0.41
▸ CDK7 P50613 1/20 0.41
▸ CDK9 P50750 1/20 0.41
▸ CCNH P51946 1/20 0.41
▸ MAP3K5 Q99683 1/20 0.41
▸ ADORA2A P29274 1/20 0.39
▸ ADORA1 P30542 1/20 0.39
▸ CCNA2 P20248 6/20 0.38
▸ CCNA1 P78396 6/20 0.38
▸ MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Aminopurine SCHEMBL5634 0.98 ALDH1A1 (1.00) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL28208518 0.96 ALDH1A1 (0.96) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL31379734 0.96 ALDH1A1 (0.96) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL357699 0.96 ALDH1A1 (0.96) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL29056388 0.96 ALDH1A1 (0.96) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL28075430 0.96 ALDH1A1 (0.96) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL6056061 0.94 ALDH1A1 (0.92) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL1528159 0.89 ALDH1A1 (0.82) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL8552158 0.87 ALDH1A1 (0.79) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL4342854 0.87 ALDH1A1 (0.79) ALDH1A1RXFP1KDM4EPDPK1GDA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1551839-B1 PROCESS FOR PREPARING 9-¬4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL -2-AMINOPURINE KYUNGDONG PHARM CO LTD (KR) 2010-02-17 — — EP disclosed
US-7041823-B2 Process for preparing 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine KYUNGDONG PHARM. CO., LTD. (KR) 2006-05-09 — — US disclosed
US-20050222413-A1 Process for preparing 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine KYUNGDONG PHARM CO., LTD. (KR) 2005-10-06 — — US disclosed
EP-1551839-A1 PROCESS FOR PREPARING 9-[4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL]-2-AMINOPURINE Kyungdong Pharm. Co., Ltd. (KR) 2005-07-13 — — EP disclosed
WO-2004007497-A1 PROCESS FOR PREPARING 9-[4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL]-2-AMINOPURINE KYUNGDONG PHARM. CO., LTD. (KR) 2004-01-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222413-A1 Process for preparing 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine TPMT, TYMP, MTAP ALDH1A1 314/4885RXFP1 4865/4885KDM4E 370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.