2-Aminopurine

2-Aminopurine

SCHEMBL5634

Nc1ncc2[nH]cnc2n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 1.00
RXFP1 Q9HBX9 1/20 0.74
KDM4E B2RXH2 2/20 0.59
PDPK1 O15530 1/20 0.48
GDA Q9Y2T3 1/20 0.48
CDK2 P24941 9/20 0.46
DPP4 P27487 1/20 0.46
PAK1 Q13153 1/20 0.44
CDK1 P06493 7/20 0.42
CCNB1 P14635 7/20 0.42
CCNT1 O60563 1/20 0.42
CDK7 P50613 1/20 0.42
CDK9 P50750 1/20 0.42
CCNH P51946 1/20 0.42
MAP3K5 Q99683 1/20 0.42
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
CCNA2 P20248 6/20 0.39
CCNA1 P78396 6/20 0.39
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Aminopurine SCHEMBL3144589 0.98 ALDH1A1 (0.96) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL28208518 0.98 ALDH1A1 (0.96) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL31379734 0.98 ALDH1A1 (0.96) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL357699 0.98 ALDH1A1 (0.96) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL29056388 0.98 ALDH1A1 (0.96) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL28075430 0.98 ALDH1A1 (0.96) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL6056061 0.96 ALDH1A1 (0.92) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL1528159 0.91 ALDH1A1 (0.82) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL8552158 0.89 ALDH1A1 (0.79) ALDH1A1RXFP1KDM4EPDPK1GDA
2-Aminopurine SCHEMBL4342854 0.89 ALDH1A1 (0.79) ALDH1A1RXFP1KDM4EPDPK1GDA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 31042 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
WO-2026106907-A1 FAST PCR BY TANDEM PRIMER EMBEDDED WITH RIBONUCLEOTIDE CEPHEID (US) 2026-05-21 WO claimed
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 US claimed
US-20260139331-A1 HIGH-THROUGHPUT METHODS FOR ISOLATING AND CHARACTERIZING AMMONIUM-EXCRETING MUTANT LIBRARIES GENERATED BY CHEMICAL MUTAGENESIS PIVOT BIO INC (US) 2026-05-21 US claimed
WO-2026099316-A1 COMPOUNDS AND METHODS FOR REDUCING ARHGEF6 EXPRESSION ASTRAZENECA AB (SE) 2026-05-15 WO claimed
CN-122004239-A Durian flower forcing agent, preparation method and application 中国热带农业科学院热带作物品种资源研究所 2026-05-12 CN claimed
US-12618064-B2 Acetylated ribonucleic acids and uses thereof HELIX NANOTECHNOLOGIES INC (US) 2026-05-05 US claimed
US-20260117214-A1 Prime Editing Systems having pegRNA with Reduced Auto-inhibitory Interaction UNIV MASSACHUSETTS (US) 2026-04-30 US claimed
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION TRILINK BIOTECHNOLOGIES, LLC (US) 2026-04-23 US claimed
EP-0309491-A1 ANTIVIRAL AGENTS SRI INTERNATIONAL (US) 1989-04-05 EP claimed
WO-1988009796-A1 NUCLEOSIDE ANALOGUES GENENTECH, INC. (US) 1988-12-15 WO claimed
WO-1988005438-A1 ANTIVIRAL AGENTS SRI INTERNATIONAL (US) 1988-07-28 WO claimed
EP-0269947-A1 Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) 1988-06-08 EP claimed
CN-85106211-A Antistaling agent for cut-flower 1987-04-01 CN claimed
EP-0105360-A4 ANTIBODIES HAVING DUAL SPECIFICITIES, THEIR PREPARATION AND USES THEREFOR. HYBRITECH INC (US) 1986-07-08 EP claimed
EP-0105360-A1 ANTIBODIES HAVING DUAL SPECIFICITIES, THEIR PREPARATION AND USES THEREFOR HYBRITECH INCORPORATED (US) 1984-04-18 EP claimed
EP-0098122-A2 Processes for producing L-proline by fermentation KYOWA HAKKO KOGYO CO., LTD. (JP) 1984-01-11 EP claimed
WO-1983003679-A1 ANTIBODIES HAVING DUAL SPECIFICITIES, THEIR PREPARATION AND USES THEREFOR HYBRITECH INC (US) 1983-10-27 WO claimed
US-4400463-A Silver chloride emulsions of modified crystal habit and processes for their preparation EASTMAN KODAK COMPANY (US) 1983-08-23 US claimed