Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | FURIN | P09958 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.40 |
| ▸ | MASP2 | O00187 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432859 | 1.00 | NAMPT (0.43) | NAMPTFURINCTSSCTSKMEN1 | |
| SCHEMBL3153543 | 0.90 | FURIN (0.43) | NAMPTFURINKLKB1MASP2PSMB5 | |
| SCHEMBL3153517 | 0.90 | FURIN (0.43) | NAMPTFURINKLKB1MASP2PSMB5 | |
| SCHEMBL1901309 | 0.84 | NAMPT (0.46) | NAMPTFURINCTSSCTSKMEN1 | |
| SCHEMBL1904039 | 0.84 | NAMPT (0.46) | NAMPTFURINCTSSCTSKMEN1 | |
| SCHEMBL1904034 | 0.84 | NAMPT (0.46) | NAMPTFURINCTSSCTSKMEN1 | |
| SCHEMBL1906161 | 0.84 | NAMPT (0.46) | NAMPTFURINCTSSCTSKMEN1 | |
| SCHEMBL3150277 | 0.84 | NAMPT (0.45) | NAMPTFURINCTSSCTSKMEN1 | |
| SCHEMBL3150292 | 0.84 | NAMPT (0.45) | NAMPTFURINCTSSCTSKMEN1 | |
| SCHEMBL1432647 | 0.83 | NAMPT (0.46) | NAMPTFURINCTSSCTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | VANTIA LIMITED (GB) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | CHRM1, ARG1, ARG2 | NAMPT 1657/4885FURIN 2416/4885CTSS 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.