Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | AGXT | P21549 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | EEF2K | O00418 | 1/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31448377 | 0.91 | MPO (0.36) | HTR2ASLC6A4KCNH2P2RX7DPP4 | |
| SCHEMBL31448529 | 0.88 | P2RX7 (0.34) | HTR2ASLC6A4KCNH2P2RX7 | |
| SCHEMBL31448532 | 0.80 | GRM2 (0.38) | HTR2ASLC6A4KCNH2P2RX7GRM2 | |
| SCHEMBL31448445 | 0.79 | TAAR1 (0.40) | IDO1AGXTGRM2MPO | |
| SCHEMBL30772359 | 0.79 | HTR2A (0.38) | HTR2ASLC6A4KCNH2P2RX7 | |
| SCHEMBL31448506 | 0.78 | L3MBTL1 (0.40) | IDO1MPO | |
| SCHEMBL30772375 | 0.74 | HTR2A (0.38) | HTR2ASLC6A4KCNH2P2RX7DPP4 | |
| SCHEMBL31448540 | 0.73 | HTR2A (0.36) | HTR2ASLC6A4KCNH2P2RX7 | |
| SCHEMBL31448574 | 0.72 | HTT (0.41) | HTR2AIDO1MPO | |
| SCHEMBL189219 | 0.68 | HTR2A (0.39) | HTR2ASLC6A4KCNH2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119343332-A | 3, 4-Dihydro-quinolin-2 (1H) -one compounds | 橘生药品工业株式会社 | 2025-01-21 | — | — | CN | disclosed |