Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31448677 | 0.87 | ALDH1A1 (0.37) | ALDH1A1RAB9ALMNAPOLBGAA | |
| SCHEMBL31448696 | 0.86 | ALDH1A1 (0.35) | ALDH1A1RAB9ALMNAPOLBGAA | |
| SCHEMBL31448734 | 0.85 | ALDH1A1 (0.35) | ALDH1A1LMNAPOLBGAAMAPT | |
| SCHEMBL31448703 | 0.84 | ALDH1A1 (0.34) | ALDH1A1LMNAGAAMAPTSMN1; SMN2 | |
| SCHEMBL30774766 | 0.83 | ALDH1A1 (0.53) | HRH3HRH4ALDH1A1RAB9ALMNA | |
| SCHEMBL31448717 | 0.83 | ALDH1A1 (0.33) | ALDH1A1GAATRPV1MAPTTSHR | |
| SCHEMBL30774675 | 0.78 | HRH3 (0.34) | HRH3HRH4ALDH1A1CHEK1NTRK1 | |
| SCHEMBL30774808 | 0.77 | LMNA (0.44) | ALDH1A1CHEK1NTRK1FYNRET | |
| SCHEMBL31448694 | 0.77 | MAPT (0.37) | ALDH1A1RAB9ALMNAGAAMAPT | |
| SCHEMBL31448733 | 0.77 | HSD11B1 (0.34) | ALDH1A1LMNAGAATRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654312-A | Substituted tetrazolyl compounds useful as T cell activators | 百时美施贵宝公司 | 2025-03-18 | — | — | CN | claimed |