Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3865262 | 0.84 | SMN1; SMN2 (0.39) | APAF1SMN1; SMN2ASAH1LMNAEGLN1 | |
| SCHEMBL18585038 | 0.83 | ASAH1 (0.39) | SMN1; SMN2ASAH1LMNAEGLN1 | |
| SCHEMBL28578142 | 0.83 | L3MBTL1 (0.40) | GABRA1GABRB2GABRG2GABRB3GABRA2 | |
| SCHEMBL9165297 | 0.80 | GABRA1 (0.36) | GABRA1GABRB2APAF1SMN1; SMN2GABRG2 | |
| SCHEMBL14518827 | 0.80 | GABRA1 (0.43) | GABRA1GABRB2GABRG2GABRB3GABRA2 | |
| SCHEMBL13030042 | 0.79 | GABRA1 (0.38) | GABRA1GABRB2APAF1GABRG2GABRB3 | |
| SCHEMBL31450499 | 0.78 | PTGER1 (0.35) | SMN1; SMN2PTGER1LMNA | |
| SCHEMBL31450492 | 0.78 | HRH4 (0.35) | GABRA1GABRB2LMNAEGLN1HRH4 | |
| SCHEMBL31450552 | 0.76 | PDE3B (0.38) | APAF1SMN1; SMN2LMNAEGLN1 | |
| SCHEMBL31450329 | 0.76 | GABRA1 (0.43) | GABRA1GABRB2GABRG2GABRB3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219460-B1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | SITARI PHARMA INC (US) | 2025-02-26 | — | — | EP | claimed |