Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1692172 | 0.86 | TSHR (0.50) | GABRA1GABRB2NOTUMALDH1A1MAPT | |
| SCHEMBL378971 | 0.81 | NOTUM (0.42) | NOTUMALDH1A1MAPTKDM4E | |
| SCHEMBL26673425 | 0.80 | ALDH1A1 (0.43) | NOTUMALDH1A1MAPTRECQLPTGS2 | |
| SCHEMBL26673429 | 0.80 | ALDH1A1 (0.43) | NOTUMALDH1A1MAPTRECQLPTGS2 | |
| SCHEMBL3169084 | 0.80 | NOTUM (0.45) | NOTUMALDH1A1MAPTKDM4E | |
| SCHEMBL27716127 | 0.78 | OXER1 (0.47) | NOTUMCNR2PPARGPPARA | |
| SCHEMBL31450403 | 0.76 | OXER1 (0.44) | GABRA1GABRB2NOTUMNTSR1GABRG2 | |
| SCHEMBL31450147 | 0.76 | GABRA1 (0.43) | GABRA1GABRB2PTGER1GABRG2GABRB3 | |
| SCHEMBL3165900 | 0.76 | POLB (0.43) | NOTUM | |
| SCHEMBL3176750 | 0.75 | HTR6 (0.39) | NOTUMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219460-B1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | SITARI PHARMA INC (US) | 2025-02-26 | — | — | EP | claimed |