Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900737 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL7953398 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL6707567 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL3902058 | 0.72 | ESR1 (0.56) | ALDH1A1MAPTL3MBTL1ESR1CES2 | |
| SCHEMBL1035354 | 0.72 | ESR1 (0.56) | ALDH1A1MAPTL3MBTL1ESR1CES2 | |
| SCHEMBL11844374 | 0.72 | ESR1 (0.56) | ALDH1A1MAPTL3MBTL1ESR1CES2 | |
| SCHEMBL11673177 | 0.72 | NPSR1 (0.52) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL13125584 | 0.72 | CES2 (0.47) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL13580073 | 0.71 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL23278527 | 0.70 | ESR1 (0.61) | ALDH1A1MAPTL3MBTL1ESR1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642028-B2 | surface layers are a polymeric composition including a resin and a cyclic polymers such as polyethylene terephthalate, acrylic acid-ethylene copolymer, styrene-co-maleic anhydride copolymer; polyhexamethylene adipamide etc. and cyclic poly(bisphenol A carbonate), cyclic poly(bisphenol C carbonate) etc. | XEROX CORPORATION (US) | 2010-01-05 | — | — | US | claimed |
| US-20080299484-A1 | contacting binder resin, pigment and liquid to form Newtonian millbase, centrifuging to remove large particles and obtain supernatant, concentrating by recentrifugation, removing supernatant | XEROX CORPORATION | 2008-12-04 | — | — | US | claimed |
| US-20060240345-A1 | Photoreceptors | XEROX CORPORATION | 2006-10-26 | — | — | US | claimed |
| US-20060210894-A1 | Imaging members | XEROX CORPORATION | 2006-09-21 | — | — | US | claimed |
| US-7052813-B2 | Imaging member | XEROX CORPORATION (US) | 2006-05-30 | — | — | US | claimed |
| US-20050271958-A1 | Imaging member | XEROX CORPORATION | 2005-12-08 | — | — | US | claimed |
| US-6933089-B2 | comprises dual charge transport layer comprising photogenerating layer, binder, and hindered phenol dopant; photoreceptors; improved electrical performance/print quality | XEROX CORPORATION (US) | 2005-08-23 | — | — | US | claimed |
| US-6797445-B2 | COMPRISES A SUBSTRATE SUPPORT, AN ELECTRICALLY CONDUCTIVE LAYER, AN OPTIONAL CHARGE BLOCKING LAYER, AN OPTIONAL ADHESIVE LAYER, A CHARGE GENERATING LAYER, A CHARGE TRANSPORT LAYER, AND A PROTECTIVE OR OVERCOATING LAYER(S) | XEROX CORPORATION | 2004-09-28 | — | — | US | claimed |
| US-20040115543-A1 | Imaging member | XEROX CORPORATION | 2004-06-17 | — | — | US | claimed |
| US-20040115546-A1 | Coating substrate with charge transfer compound and antioxidant ; wear resistant, electrical properties | XEROX CORPORATION | 2004-06-17 | — | — | US | claimed |
| US-20040115544-A1 | Imaging member | XEROX CORPORATION | 2004-06-17 | — | — | US | claimed |
| US-20040115545-A1 | Imaging members | XEROX CORPORATION | 2004-06-17 | — | — | US | claimed |
| US-20040002013-A1 | Blue diode laser sensitive photoreceptor | XEROX CORPORATION | 2004-01-01 | — | — | US | claimed |
| EP-1715008-B1 | Phthalocyanine co-crystals for use in photoreceptors | XEROX CORP (US) | 2012-10-03 | — | — | EP | disclosed |
| US-7799501-B2 | Photoreceptors | XEROX CORPORATION (US) | 2010-09-21 | — | — | US | disclosed |
| US-20090281291-A1 | IMAGING MEMBERS | XEROX CORPORATION (US) | 2009-11-12 | — | — | US | disclosed |
| US-20040018440-A1 | Imaging members | XEROX CORPORATION | 2004-01-29 | — | — | US | disclosed |
| US-20040018439-A1 | Imaging members | XEROX CORPORATION | 2004-01-29 | — | — | US | disclosed |
| US-20040009418-A1 | Imaging members | XEROX CORPORATION. | 2004-01-15 | — | — | US | disclosed |
| US-6656650-B1 | Imaging members | XEROX CORPORATION | 2003-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281291-A1 | IMAGING MEMBERS | VCL, MAP1LC3C, MAP1LC3B | ALDH1A1 4230/4885KMT2A 2441/4885MEN1 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.