Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 11/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601227 | 0.71 | AHR (1.00) | AHRCYP11B2CYP11B1APPCSNK1D | |
| SCHEMBL31451563 | 0.71 | CSNK1D (0.41) | AHRCSNK1DCSNK1E | |
| SCHEMBL31451448 | 0.70 | NUDT1 (0.35) | AHRCYP11B2 | |
| SCHEMBL30601186 | 0.68 | AHR (1.00) | AHRAPP | |
| SCHEMBL30601225 | 0.68 | AHR (1.00) | AHRCYP11B2CYP11B1PIK3CG | |
| SCHEMBL24782810 | 0.68 | AHR (0.46) | AHRCYP11B2CYP11B1 | |
| SCHEMBL30601215 | 0.67 | AHR (1.00) | AHRAPPPIK3CG | |
| SCHEMBL43051 | 0.66 | AHR (0.58) | AHRAPPPIK3CG | |
| SCHEMBL618586 | 0.66 | AHR (0.60) | AHRAPPPIK3CG | |
| SCHEMBL31451683 | 0.66 | APP (0.56) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054187-A1 | TGR5 ANTAGONISTS AND METHODS OF USE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2025-03-13 | — | — | WO | disclosed |