SCHEMBL31452

SCHEMBL31452

CCCc1ccc(CO)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LPL P06858 2/20 0.56
▸ LIPG Q9Y5X9 2/20 0.56
▸ THRB P10828 2/20 0.48
▸ PLK1 P53350 1/20 0.48
▸ CNR1 P21554 1/20 0.48
▸ CNR2 P34972 1/20 0.48
▸ CA2 P00918 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ CHKA P35790 1/20 0.45
▸ MGLL Q99685 1/20 0.43
▸ ESR1 P03372 2/20 0.43
▸ ADRA2A P08913 2/20 0.43
▸ ADORA3 P0DMS8 2/20 0.43
▸ TACR2 P21452 2/20 0.43
▸ SLC6A2 P23975 2/20 0.43
▸ SLC6A4 P31645 2/20 0.43
▸ SLC6A3 Q01959 2/20 0.43
▸ KDM4E B2RXH2 2/20 0.43
▸ ALDH1A1 P00352 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL9650054 0.97 LPL (0.54) LPLLIPGTHRBPLK1CNR1
SCHEMBL1967849 0.93 LPL (0.50) LPLLIPGTHRBPLK1CNR1
SCHEMBL142480 0.85 LPL (0.62) LPLLIPGTHRBPLK1CNR1
SCHEMBL358689 0.84 CA2 (0.59) LPLLIPGTHRBPLK1CA2
SCHEMBL7643947 0.83 CA2 (0.59) LPLLIPGTHRBPLK1CNR1
Hydroxyamine SCHEMBL17181093 0.82 LPL (0.61) LPLLIPGTHRBPLK1CNR1
SCHEMBL357024 0.82 ESR1 (0.65) LPLLIPGMGLLESR1ADRA2A
SCHEMBL9839848 0.82 LPL (0.59) LPLLIPGTHRBPLK1CNR1
SCHEMBL7539245 0.82 CHKA (0.58) CA2TSHRCHKAESR1
Ammonia Solution, Strong SCHEMBL9651935 0.81 CA2 (0.56) LPLLIPGTHRBPLK1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 826 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025053791-A1 ONE-POT GRAFTING OF POLYMERS FROM ALCOHOLS AND BIOMASSES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-03-13 — — WO claimed
CN-118479961-A Synthesis method of p-n-propyl benzaldehyde 湖北大学 2024-08-13 — — CN claimed
WO-2005079573-A1 ANTIFUNGAL COMPOSITIONS GIVAUDAN SA (CH) 2005-09-01 — — WO claimed
WO-2025053791-A1 ONE-POT GRAFTING OF POLYMERS FROM ALCOHOLS AND BIOMASSES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-03-13 — — WO disclosed
CN-118955244-A Method for preparing primary alcohol by homogeneously catalyzing and reducing carboxylic acid derivative by using N-heterocyclic carbene copper complex 延安大学 2024-11-15 — — CN disclosed
US-20240299559-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF MONTE ROSA THERAPEUTICS AG (CH) 2024-09-12 — — US disclosed
CN-118479961-A Synthesis method of p-n-propyl benzaldehyde 湖北大学 2024-08-13 — — CN disclosed
CN-118479961-A Synthesis method of p-n-propyl benzaldehyde 湖北大学 2024-08-13 — — CN disclosed
US-12024536-B2 C-terminal HSP90 inhibitors UNIVERSITY OF KANSAS (US) 2024-07-02 — — US disclosed
US-12018093-B2 Hemiasterlin derivatives and antibody-drug conjugates including same Sumitomo Pharma Co., Ltd. (JP) 2024-06-25 — — US disclosed
CN-113387055-B Film, method for producing film, and bag 住友化学株式会社 2024-06-07 — — CN disclosed
US-4474879-A Process for 3-hydroxymethyl cephalosporin sulfones ELI LILLY AND COMPANY (US) 1984-10-02 — — US disclosed
US-4459405-A Desacetylcephalosporin sulfones ELI LILLY AND COMPANY (US) 1984-07-10 — — US disclosed
EP-0109816-A1 N-substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process ELI LILLY AND COMPANY (US) 1984-05-30 — — EP disclosed
EP-0109301-A2 7-(S)-acylaminocephalosporin sulfones and process ELI LILLY AND COMPANY (US) 1984-05-23 — — EP disclosed
EP-0109300-A2 Desacetylcephalosporin sulfones ELI LILLY AND COMPANY (US) 1984-05-23 — — EP disclosed
US-4436596-A N-Substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process ELI LILLY AND COMPANY (US) 1984-03-13 — — US disclosed
EP-0004881-B1 PROCESS FOR THE PREPARATION OF AROMATIC AND ARALIPHATIC ALDEHYDES BASF Aktiengesellschaft (DE) 1981-10-07 — — EP disclosed
US-4224254-A OXIDATION OF AROMATIC ALCOHOLS, SILVER CATALYST BASF AKTIENGESELLSCHAFT (DE) 1980-09-23 — — US disclosed
EP-0004881-A2 Process for the preparation of aromatic and araliphatic aldehydes BASF Aktiengesellschaft (DE) 1979-10-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240299559-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF CDK2, SKP2, CDK1 LPL 4176/4885LIPG 4024/4885THRB 2551/4885
US-12024536-B2 C-terminal HSP90 inhibitors HSP90AB2P, HSP90AB1, HSP90B1 LPL 1939/4885LIPG 1183/4885THRB 2412/4885
US-12018093-B2 Hemiasterlin derivatives and antibody-drug conjugates including same FCGRT, QARS1, INHA LPL 4047/4885LIPG 4222/4885THRB 2138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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