Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | P4HB | P07237 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31452350 | 0.87 | CYP1A1 (0.37) | MAPK1GABRA1GABRB2MEN1LMNA | |
| SCHEMBL31452292 | 0.77 | HTR2A (0.35) | P4HB | |
| SCHEMBL31452409 | 0.73 | POLL (0.37) | TSHRHSD17B10GABRA1GABRB2MEN1 | |
| SCHEMBL31452272 | 0.73 | DYRK1A (0.38) | KRASHSD17B10KMT2A | |
| SCHEMBL18786964 | 0.64 | MKNK2 (0.46) | KRASKMT2A | |
| SCHEMBL13904591 | 0.63 | CYP3A4 (0.39) | TSHRHSD17B10MEN1LMNACYP3A4 | |
| SCHEMBL13904588 | 0.63 | CYP3A4 (0.39) | TSHRHSD17B10MEN1LMNACYP3A4 | |
| SCHEMBL6249889 | 0.63 | KDM1A (0.42) | GABRA1GABRB2LMNA | |
| SCHEMBL31452313 | 0.62 | METAP1 (0.36) | MEN1LMNACYP3A4ALOX15KMT2A | |
| SCHEMBL26568794 | 0.58 | CHRM2 (0.37) | TSHRMEN1KMT2ARPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066306-A1 | COMPOUNDS FOR TREATING MICROBIAL INFECTIONS, METHODS OF MAKING AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2025-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066306-A1 | COMPOUNDS FOR TREATING MICROBIAL INFECTIONS, METHODS OF MAKING AND USES THEREOF | ATF4, ATF1, CGAS | KRAS 1729/4885MAPK1 1246/4885AKR1C3 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.