Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.35 |
| ▸ | HTR2C | P28335 | 10/20 | 0.35 |
| ▸ | HTR2B | P41595 | 10/20 | 0.35 |
| ▸ | P4HB | P07237 | 3/20 | 0.33 |
| ▸ | PDIA4 | P13667 | 2/20 | 0.33 |
| ▸ | PDIA3 | P30101 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.30 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31452409 | 0.87 | POLL (0.37) | HTR2AHTR2CHTR2BPOLB | |
| SCHEMBL31452279 | 0.77 | KRAS (0.34) | P4HB | |
| SCHEMBL31452350 | 0.73 | CYP1A1 (0.37) | — | |
| SCHEMBL31452289 | 0.73 | HTR2A (0.35) | HTR2AHTR2CHTR2BPOLBMAOA | |
| SCHEMBL31452285 | 0.62 | POLL (0.44) | HTR2AHTR2CHTR2BPOLB | |
| SCHEMBL3170686 | 0.58 | SMN1; SMN2 (0.50) | POLB | |
| SCHEMBL9617994 | 0.58 | CHRM2 (0.38) | POLB | |
| SCHEMBL6249889 | 0.57 | KDM1A (0.42) | — | |
| SCHEMBL22866536 | 0.57 | CA2 (0.47) | — | |
| SCHEMBL17205762 | 0.57 | CA2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066306-A1 | COMPOUNDS FOR TREATING MICROBIAL INFECTIONS, METHODS OF MAKING AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2025-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066306-A1 | COMPOUNDS FOR TREATING MICROBIAL INFECTIONS, METHODS OF MAKING AND USES THEREOF | ATF4, ATF1, CGAS | HTR2A 3864/4885HTR2C 3784/4885HTR2B 4215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.