Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8235252 | 0.79 | KEAP1 (0.47) | KEAP1NFE2L2KHKTDP1 | |
| SCHEMBL23620152 | 0.77 | KEAP1 (0.41) | KEAP1NFE2L2KHKTDP1 | |
| SCHEMBL29829949 | 0.77 | KEAP1 (0.41) | KEAP1NFE2L2KHKTDP1 | |
| SCHEMBL30296610 | 0.74 | KEAP1 (0.38) | KEAP1NFE2L2KHKTDP1 | |
| SCHEMBL21609199 | 0.74 | KEAP1 (0.42) | KEAP1NFE2L2KHKTDP1 | |
| SCHEMBL12608076 | 0.74 | KEAP1 (0.38) | KEAP1NFE2L2KHKTDP1 | |
| SCHEMBL30410994 | 0.74 | KHK (0.44) | KEAP1NFE2L2KHK | |
| SCHEMBL23970967 | 0.74 | KHK (0.44) | KEAP1NFE2L2KHK | |
| SCHEMBL24496554 | 0.74 | CD44 (0.43) | TDP1 | |
| SCHEMBL26712680 | 0.74 | KEAP1 (0.38) | KEAP1NFE2L2KHKTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025051157-A1 | PYRIDINE-2(1H)-KETONE PRMT5-MTA INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2025-03-13 | — | — | WO | disclosed |