SCHEMBL3145352

SCHEMBL3145352

CCCCCCCCCCOC1CCCS1(=O)=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.38
HTT P42858 2/20 0.38
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GBA1 P04062 3/20 0.38
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
RECQL P46063 2/20 0.34
CES2 O00748 2/20 0.34
GLA P06280 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
EPHX2 P34913 1/20 0.34
BLM P54132 1/20 0.34
NAAA Q02083 3/20 0.33
MEN1 O00255 1/20 0.32
THRB P10828 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPT P10636 1/20 0.32
LPAR1 Q92633 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9186742 1.00 MAPK1 (0.38) MAPK1HTTGAASMN1; SMN2GBA1
SCHEMBL20601578 0.77 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1
SCHEMBL4980304 0.69 GAA (0.51) MAPK1HTTGAASMN1; SMN2GBA1
SCHEMBL424520 0.69 GAA (0.51) MAPK1HTTGAASMN1; SMN2GBA1
SCHEMBL11099263 0.69 GAA (0.51) MAPK1HTTGAASMN1; SMN2GBA1
SCHEMBL3181641 0.67 GBA1 (0.49) MAPK1HTTGBA1ALDH1A1TDP1
SCHEMBL19678784 0.67 GBA1 (0.49) MAPK1HTTGBA1ALDH1A1TDP1
SCHEMBL3172563 0.67 GBA1 (0.49) MAPK1HTTGBA1ALDH1A1TDP1
SCHEMBL3181823 0.67 GBA1 (0.49) MAPK1HTTGBA1ALDH1A1TDP1
SCHEMBL8641844 0.67 NAAA (0.48) MAPK1HTTGBA1ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2046926-B1 MULTI-DISPERSANT LUBRICATING COMPOSITION LUBRIZOL CORP (US) 2018-06-13 EP disclosed
US-8598099-B2 Multi-dispersant lubricating composition THE LUBRIZOL CORPORATION (US) 2013-12-03 US disclosed
US-20130102511-A1 Additive Concentrate and a Method of Lubricating Transmissions THE LUBRIZOL CORPORATION (US) 2013-04-25 US disclosed
US-20120178661-A1 Additive Concentrate and a Method of Lubricating Transmissions THE LUBRIZOL CORPORATION (US) 2012-07-12 US disclosed
US-20120135898-A1 Multi-Dispersant Lubricating Composition THE LUBRIZOL CORPORATION (US) 2012-05-31 US disclosed
US-20100099593-A1 Additive Concentrate and a Method of Lubricating Transmissions THE LUBRIZOL CORPORATION 2010-04-22 US disclosed
EP-1200541-B1 NITROGEN-CONTAINING ESTERIFIED CARBOXY-CONTAINING INTERPOLYMERS HAVING ENHANCED OXIDATIVE STABILITY AND LUBRICANTS CONTAINING THEM LUBRIZOL CORP (US) 2010-02-10 EP disclosed
US-20090305919-A1 Multi-Dispersant Lubricating Composition THE LUBRIZOL CORPORATION (US) 2009-12-10 US disclosed
EP-2046926-A2 MULTI-DISPERSANT LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2009-04-15 EP disclosed
WO-2008115726-A2 ADDITIVE CONCENTRATE AND A METHOD OF LUBRICATING TRANSMISSIONS THE LUBRIZOL CORPORATION (US) 2008-09-25 WO disclosed
WO-2008014319-A2 MULTI-DISPERSANT LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2008-01-31 WO disclosed
US-6544935-B1 Useful as viscosity improvers THE LUBRIZOL CORPORATION 2003-04-08 US disclosed
EP-1200541-A1 NITROGEN-CONTAINING ESTERIFIED CARBOXY-CONTAINING INTERPOLYMERS HAVING ENHANCED OXIDATIVE STABILITY AND LUBRICANTS CONTAINING THEM The Lubrizol Corporation (US) 2002-05-02 EP disclosed
WO-2001004242-A1 NITROGEN-CONTAINING ESTERIFIED CARBOXY-CONTAINING INTERPOLYMERS HAVING ENHANCED OXIDATIVE STABILITY AND LUBRICANTS CONTAINING THEM THE LUBRIZOL CORPORATION (US) 2001-01-18 WO disclosed