SCHEMBL31453570

SCHEMBL31453570

CCOC(=O)/C=C\C(=O)N(C)c1ccc(Cl)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.41
ALDH1A1 P00352 5/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 3/20 0.39
CYP3A4 P08684 1/20 0.38
TTR P02766 1/20 0.36
DPP4 P27487 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
MDM2 Q00987 1/20 0.35
PTGIR P43119 1/20 0.35
PTGDR Q13258 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31453677 0.90 ALDH1A1 (0.45) MAPTALDH1A1L3MBTL1LMNACYP3A4
SCHEMBL31453654 0.88 CYP3A4 (0.40) MAPTALDH1A1L3MBTL1LMNACYP3A4
SCHEMBL31453578 0.87 MAPT (0.43) MAPTALDH1A1L3MBTL1LMNACYP3A4
SCHEMBL31453580 0.86 MAPT (0.42) MAPTALDH1A1L3MBTL1LMNACYP3A4
SCHEMBL31453566 0.85 CYP3A4 (0.39) MAPTALDH1A1L3MBTL1LMNACYP3A4
SCHEMBL31453617 0.84 FDPS (0.44) MAPTALDH1A1LMNACYP3A4
SCHEMBL31453729 0.83 LMNA (0.38) MAPTALDH1A1L3MBTL1LMNACYP3A4
SCHEMBL31453543 0.83 CNKSR1 (0.37) MAPTALDH1A1L3MBTL1LMNACYP3A4
SCHEMBL31453548 0.82 NR1H4 (0.40) MAPTALDH1A1LMNACYP3A4TTR
SCHEMBL31453539 0.81 MAPT (0.43) MAPTALDH1A1LMNATTRDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025016138-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF SUZHOU EOC MEDICAL RESEARCH CO., LTD. (CN) 2025-01-23 WO disclosed