Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.67 |
| ▸ | MGAM | O43451 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | SI | P14410 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | ERN1 | O75460 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29276289 | 0.88 | MAOB (0.63) | MAOBMAPTLMNAGAAALDH1A1 | |
| SCHEMBL4383562 | 0.88 | MAOB (0.67) | MAOBMAPTLMNAGAAALDH1A1 | |
| SCHEMBL29749855 | 0.88 | MAOB (0.67) | MAOBMAPTLMNAGAAALDH1A1 | |
| SCHEMBL660434 | 0.85 | ALDH1A1 (0.69) | MAOBMAPTLMNAGAAALDH1A1 | |
| SCHEMBL31262908 | 0.84 | MAOA (0.63) | MAOBMAPTLMNAGAAALDH1A1 | |
| SCHEMBL31454846 | 0.83 | ERAP1 (0.54) | MAOBMAPTLMNAGAAALDH1A1 | |
| SCHEMBL11701538 | 0.82 | MAOB (0.60) | MAOBMAPTLMNAGAAALDH1A1 | |
| SCHEMBL6333867 | 0.81 | MAOB (0.61) | MAOBMAPTLMNAGAAALDH1A1 | |
| 4-Methyldaphnetin SCHEMBL1065373 | 0.80 | MCL1 (1.00) | MAOBMAPTLMNAGAAALDH1A1 | |
| SCHEMBL4187220 | 0.80 | MAOB (1.00) | MAOBMAPTLMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025042896-A1 | DNA TOPOISOMERASE IIβ INHIBITORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2025-02-27 | — | — | WO | disclosed |