Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455361 | 0.91 | ADORA1 (0.40) | POLBCTDSP1KMT2ANPC1RAB9A | |
| SCHEMBL31454994 | 0.88 | TNIK (0.36) | KMT2AMEN1LMNATNIKALDH1A1 | |
| SCHEMBL31455145 | 0.87 | CYP3A4 (0.33) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL31455019 | 0.87 | GSK3A (0.34) | NPC1ABCB1ABCC1 | |
| SCHEMBL31455406 | 0.86 | CYP3A4 (0.34) | NPC1MAPTABCB1ABCC1 | |
| SCHEMBL31455107 | 0.79 | BRD9 (0.41) | POLBCTDSP1KMT2ANPC1RAB9A | |
| SCHEMBL31455364 | 0.78 | ADORA1 (0.42) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL31455449 | 0.78 | GSK3B (0.39) | NPC1MAPTSMN1; SMN2LMNAABCB1 | |
| SCHEMBL31455204 | 0.76 | GSK3B (0.38) | NPC1ABCB1KDM4EHPGDHTT | |
| SCHEMBL31455712 | 0.73 | TSHR (0.42) | KMT2AMEN1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |