Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31454994 | 0.91 | TNIK (0.36) | ADORA1ADORA3ADORA2AHDAC1HDAC2 | |
| SCHEMBL31455361 | 0.87 | ADORA1 (0.40) | ADORA1ADORA3ADORA2AGSK3AGSK3B | |
| SCHEMBL31455694 | 0.85 | HDAC1 (0.46) | ADORA1ADORA3ADORA2AHDAC1HDAC2 | |
| SCHEMBL31455411 | 0.85 | HDAC1 (0.46) | ADORA1ADORA3ADORA2AHDAC1HDAC2 | |
| SCHEMBL31455325 | 0.81 | HDAC1 (0.41) | ADORA1ADORA3ADORA2AHDAC1HDAC2 | |
| SCHEMBL31455141 | 0.78 | POLB (0.36) | EGFRROS1ALKLMNAHTT | |
| SCHEMBL31455274 | 0.77 | HDAC1 (0.38) | ADORA1ADORA3ADORA2AHDAC1HDAC2 | |
| SCHEMBL31455285 | 0.76 | HDAC2 (0.40) | ADORA1ADORA3ADORA2AHDAC1HDAC2 | |
| SCHEMBL31455366 | 0.75 | ALDH1A1 (0.61) | HDAC1HDAC2HTTNPC1RAB9A | |
| SCHEMBL31455390 | 0.74 | HDAC2 (0.56) | HDAC1HDAC2GSK3BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |