Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455019 | 0.94 | GSK3A (0.34) | CYP3A4CYP2C9CYP2C19NPSR1ABCB1 | |
| SCHEMBL31455145 | 0.88 | CYP3A4 (0.33) | CYP3A4CYP2C9CYP2C19NPSR1ABCB1 | |
| SCHEMBL31455487 | 0.87 | HDAC1 (0.36) | GSK3AGSK3BADORA2AADORA1ADORA3 | |
| SCHEMBL31455141 | 0.86 | POLB (0.36) | ABCB1NPC1ABCC1MAPT | |
| SCHEMBL31455204 | 0.84 | GSK3B (0.38) | ABCB1NPC1GSK3AGSK3BADORA2A | |
| SCHEMBL31455274 | 0.81 | HDAC1 (0.38) | GSK3AGSK3BADORA2AADORA1ADORA3 | |
| SCHEMBL31455069 | 0.79 | GSK3A (0.35) | ABCB1GSK3AGSK3BADORA2AADORA1 | |
| SCHEMBL31455449 | 0.78 | GSK3B (0.39) | CYP3A4CYP2C9CYP2C19NPSR1ABCB1 | |
| SCHEMBL31455361 | 0.77 | ADORA1 (0.40) | NPC1GSK3AGSK3BADORA2AADORA1 | |
| SCHEMBL31455285 | 0.74 | HDAC2 (0.40) | GSK3AGSK3BADORA2AADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |