Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455401 | 1.00 | MAPT (0.43) | MAPTTDP1NOS3NOS1NOS2 | |
| SCHEMBL31455469 | 0.88 | MAPT (0.43) | MAPTTDP1NOS3NOS1NOS2 | |
| SCHEMBL31455310 | 0.88 | MAPT (0.42) | MAPTTDP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL31455436 | 0.88 | MAPT (0.42) | MAPTTDP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL31455368 | 0.88 | MAPT (0.42) | MAPTTDP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL31455549 | 0.82 | ALDH1A1 (0.36) | MAPTALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL31455336 | 0.82 | ALDH1A1 (0.36) | MAPTALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL31455109 | 0.81 | MAPT (0.43) | MAPTTDP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL31455176 | 0.81 | MAPT (0.43) | MAPTTDP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL31687192 | 0.81 | MAPT (0.43) | MAPTTDP1ALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |