Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31687192 | 0.88 | MAPT (0.43) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL30255307 | 0.88 | MAPT (0.43) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL31455109 | 0.88 | MAPT (0.43) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL31455176 | 0.88 | MAPT (0.43) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL30289535 | 0.82 | MAPT (0.56) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL31455469 | 0.80 | MAPT (0.43) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL31455365 | 0.79 | MAPT (0.41) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL31184814 | 0.78 | MAPT (0.40) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL15199158 | 0.75 | MAPT (0.46) | MAPTMEN1KMT2ALMNATDP1 | |
| SCHEMBL31184651 | 0.74 | ALDH1A1 (0.43) | MAPTMEN1KMT2APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |