Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455342 | 0.95 | ALDH1A1 (0.57) | ALDH1A1HTTTRPV1TDP1TSHR | |
| SCHEMBL31455623 | 0.86 | ALDH1A1 (0.53) | ALDH1A1HTTTRPV1TDP1TSHR | |
| SCHEMBL31455312 | 0.84 | LTA4H (0.45) | — | |
| SCHEMBL31455362 | 0.84 | ALDH1A1 (0.46) | ALDH1A1HTTTRPV1TDP1TSHR | |
| SCHEMBL31455366 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HTTTRPV1TDP1TSHR | |
| SCHEMBL31455394 | 0.78 | MAPT (0.36) | ALDH1A1TDP1HPGDMAPT | |
| SCHEMBL31455191 | 0.76 | GAA (0.61) | ALDH1A1HTTTRPV1TSHRLMNA | |
| SCHEMBL25384573 | 0.75 | ABCG2 (0.54) | ALDH1A1HPGDKMT2AMAPTMEN1 | |
| SCHEMBL31454989 | 0.75 | ABCG2 (0.54) | ALDH1A1HPGDKMT2AMAPTMEN1 | |
| SCHEMBL31455002 | 0.73 | PRMT1 (0.49) | HTTBRD4KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |