Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455274 | 0.93 | HDAC1 (0.38) | HDAC1HDAC2GSK3AGSK3BADORA1 | |
| SCHEMBL31455406 | 0.87 | CYP3A4 (0.34) | GSK3AGSK3BADORA1ADORA2AADORA3 | |
| SCHEMBL31455285 | 0.86 | HDAC2 (0.40) | HDAC1HDAC2GSK3AGSK3BADORA1 | |
| SCHEMBL31454994 | 0.84 | TNIK (0.36) | HDAC1HDAC2GSK3AGSK3BADORA1 | |
| SCHEMBL31455325 | 0.82 | HDAC1 (0.41) | HDAC1HDAC2GSK3AGSK3BADORA1 | |
| SCHEMBL31455019 | 0.82 | GSK3A (0.34) | GSK3AGSK3BADORA1ADORA2AADORA3 | |
| SCHEMBL31455491 | 0.78 | HDAC1 (0.40) | HDAC1HDAC2GSK3AGSK3BADORA1 | |
| SCHEMBL31455490 | 0.78 | HDAC1 (0.40) | HDAC1HDAC2GSK3AGSK3BADORA1 | |
| SCHEMBL31455411 | 0.76 | HDAC1 (0.46) | HDAC1HDAC2GSK3AGSK3BADORA1 | |
| SCHEMBL31455694 | 0.76 | HDAC1 (0.46) | HDAC1HDAC2GSK3AGSK3BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |