Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455411 | 1.00 | HDAC1 (0.46) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31455285 | 0.90 | HDAC2 (0.40) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31455449 | 0.86 | GSK3B (0.39) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31455364 | 0.85 | ADORA1 (0.42) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31455325 | 0.82 | HDAC1 (0.41) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31455274 | 0.78 | HDAC1 (0.38) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31455145 | 0.77 | CYP3A4 (0.33) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31455487 | 0.76 | HDAC1 (0.36) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31454994 | 0.76 | TNIK (0.36) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31455390 | 0.74 | HDAC2 (0.56) | HDAC1HDAC2GSK3BABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |