Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455344 | 0.88 | MAPT (0.43) | MAPTTDP1NOS3NOS1NOS2 | |
| SCHEMBL31455401 | 0.88 | MAPT (0.43) | MAPTTDP1NOS3NOS1NOS2 | |
| SCHEMBL31455034 | 0.82 | ALDH1A1 (0.39) | MAPTMEN1KMT2AGAATSHR | |
| SCHEMBL31455422 | 0.80 | MAPT (0.44) | MAPTTDP1MEN1KMT2ANPC1 | |
| SCHEMBL31455122 | 0.80 | MAPT (0.40) | MAPTTDP1MEN1KMT2ANOS3 | |
| SCHEMBL31455436 | 0.76 | MAPT (0.42) | MAPTTDP1NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31455310 | 0.76 | MAPT (0.42) | MAPTTDP1NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31455368 | 0.76 | MAPT (0.42) | MAPTTDP1NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8949097 | 0.75 | ALDH1A1 (0.50) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL25928005 | 0.75 | ALDH1A1 (0.50) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |