Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455855 | 0.81 | IDO1 (0.45) | MAPK1HTTRAB9ANPC1ALDH1A1 | |
| SCHEMBL31455453 | 0.79 | MAPT (0.41) | MAPK1HTTRAB9ANPC1ALDH1A1 | |
| SCHEMBL31455529 | 0.78 | MEN1 (0.43) | MAPK1HTTRAB9ANPC1ALDH1A1 | |
| SCHEMBL31455424 | 0.77 | NPC1 (0.44) | MAPK1HTTRAB9ANPC1ALDH1A1 | |
| SCHEMBL31455675 | 0.75 | MAPT (0.54) | MAPK1HTTRAB9ANPC1ALDH1A1 | |
| SCHEMBL31455162 | 0.73 | KMT2A (0.42) | RAB9ANPC1ALDH1A1MAPTTDP1 | |
| SCHEMBL31455388 | 0.71 | PRMT1 (0.46) | MAPK1HTTRAB9ANPC1ALDH1A1 | |
| SCHEMBL21467287 | 0.69 | ALDH1A1 (0.49) | MAPK1HTTRAB9ANPC1ALDH1A1 | |
| SCHEMBL6297719 | 0.69 | TDP1 (0.58) | MAPK1HTTRAB9ANPC1ALDH1A1 | |
| SCHEMBL28172411 | 0.69 | MAPK1 (0.68) | MAPK1HTTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |