Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455529 | 0.83 | MEN1 (0.43) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL31455499 | 0.80 | MAPT (0.39) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL31455855 | 0.79 | IDO1 (0.45) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL31455445 | 0.79 | MAPK1 (0.40) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL31456002 | 0.78 | MEN1 (0.49) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL31455523 | 0.77 | ABL1 (0.50) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL19781255 | 0.76 | ALDH3A1 (0.46) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL24553617 | 0.72 | MAPT (0.62) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9940716 | 0.70 | ALDH1A1 (0.51) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL4930929 | 0.70 | MAPT (0.68) | MAPTMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |