Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18380160 | 0.88 | PTPN2 (0.52) | PTPN2PTPN1PTPN6NPC1RAB9A | |
| SCHEMBL31420343 | 0.84 | PRMT1 (0.41) | NPC1RAB9AKMT2A | |
| SCHEMBL31420375 | 0.84 | NAMPT (0.51) | PTPN2PTPN1PTPN6GPR119 | |
| SCHEMBL31455264 | 0.83 | USP30 (0.39) | PTPRBUSP30GPR119HPGDSCKS1B | |
| SCHEMBL31455102 | 0.81 | NAMPT (0.45) | USP30GPR119HPGDS | |
| SCHEMBL31420326 | 0.79 | NAMPT (0.40) | PTPRBUSP30GPR119HPGDS | |
| SCHEMBL31455378 | 0.79 | HPGDS (0.44) | USP30GPR119HPGDS | |
| SCHEMBL27225984 | 0.79 | JAK2 (0.44) | PTPRBCKS1BSKP1SKP2 | |
| SCHEMBL30802461 | 0.79 | JAK2 (0.44) | PTPRBCKS1BSKP1SKP2 | |
| SCHEMBL31455038 | 0.78 | NPC1 (0.38) | NPC1RAB9AABL1LMNAGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |