Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.36 |
| ▸ | FLT1 | P17948 | 2/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455919 | 0.90 | KDM4E (0.41) | ALDH1A1PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL1418414 | 0.88 | PDGFRB (0.42) | NOTUMALDH1A1PDGFRBFGFR1PDGFRA | |
| SCHEMBL31710286 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HTTMAPTTSHR | |
| SCHEMBL23785506 | 0.83 | ALDH1A1 (0.38) | ALDH1A1HTTTSHR | |
| SCHEMBL10260913 | 0.83 | GABRG2 (0.36) | ALDH1A1HTTSCN9A | |
| SCHEMBL15543791 | 0.83 | POLB (0.45) | ALDH1A1KDM4EPKMATRHPGD | |
| SCHEMBL364791 | 0.81 | POLB (0.40) | ALDH1A1HTTHPGDMAPTGAA | |
| SCHEMBL31455679 | 0.80 | NOTUM (0.41) | NOTUMALDH1A1HTTPDGFRBFGFR1 | |
| SCHEMBL27890 | 0.79 | KDM4E (0.43) | NOTUMALDH1A1PDGFRBFGFR1PDGFRA | |
| SCHEMBL19993672 | 0.79 | MAPT (0.42) | NOTUMALDH1A1KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |